Adding some ancient ones, both of which tend toward the adult and partially gloomy:
http://brunostrip.com/ -- follows the main character Bruno over the course of quite a few years, including her hook-ups and escapades with both men and women (she gravitates more toward the latter over time), and her development as a person
http://www.nowheregirl.com/index.html -- unfinished, and will forever remain that way, but still something I like to go back to every now and again