Giving this another read over it seems like it is loosely following the actual in game events.
M4 is seperated and gets cornered by Agent and Oroborous. STAR distracts Elisa and gets infected by the Parapluie virus. After being rescued STAR goes rogue and fakes her own death in an attempt to slow down the virus. She is last seen by M16 and they both admit they are doing everything for M4's sake. M4, believing STAR is dead, becomes increasingly vindictive and loses her quiet and shy demenor.
Meanwhile, Squad 404 are "coincidentally" in the area and serve as a distraction while stumbling across and recovering STAR.
This is all being recalled mostly by memory so there's probably some incorrect information, by the basic plot remains largely the same.
Now that that's established, I'm kind of worried how Singularity and Continuum Turbulance are going to be adapted.
Then there's chapter 17 that's simply just a joke on how "corpse dragging" works and is as hilarious as it is relatable.