I've only seen that "You can't pair anyone with Zarya because she's the only lesbian" dude, but I'm sure there are folks really tied up over their preferred ships that get upset at say, Fareeha x Mei or whatever it happens to be.
And not only does she have hemorrhoids, her arm will probably fall off just like Mary's left arm apparently has in the third to last panel. It's the only explanation for why it's so far from the shoulder.
Arms falling off is just as contagious as hemorrhoids after all...