A fascinating story. I actually like this better than Shiroi Heya no Futari, which I found a tad melodramatic, but not for romance purposes. The romance here was little more than child abuse. Then again, it makes sense given its setting, as it was normal for children and adults to have sex. I do feel like there should be a warning for this in the tags, but I don't think 'lolicon' is appropriate for this kind of story since it's not porn, the relationship makes sense given the era and the manga doesn't eroticise Hatshepsut. The 'rape' tag might work given the poison.
The rest of the story was good though, and Hatshepsut was an interesting character. The art was much less ridiculous than Shiroi Heya no Futari as well.