Going from just my past experience with fictional drama, this really seems like Nene is trying to get Amane to cut her romantic feelings for her completely. And I doubt it's out of spite, I imagine she's probably doing it to protect Amane in some obscure way, even if it means Amane starting to hate her. That seems about right how this would usually go right? Seriously gonna be surprised if they subvert my expectations and those are Nene's actual honest feelings.
God I hope this is the case cause if this is Nene’s true feelings I would hate her so much. Either way a really bitchy way to do things on Nene’s part.