I just finished one route of Asphyxia (yes, I'm on a roll, I know).
While it is a well-written story about teen angst and clinical depression, it is rather short/lacking in resolution.
On Asphyxia's note, I wouldn't recommend it, specifically because of that. While the stiffness and lack of drive is indeed an appropriate representation of depression, it makes for a poor VN. I played through all (but one, I believe) routes, and it feels like your choices don't matter at all. MC starts and ends the story in mostly (or absolutely, it's been some time) the same. I was also very disappointed for not being able to sex Lady Byron.