Bit unsure about what you meant, but a bad end is very possible. Yuri Hime did mention of their intention to swap their focus.
Has Yuri Hime ever had a het ending for a series? Bad end is one thing, het ending would be a complete blindside. And I'm not inclined to feel oneshots count given that many a oneshot are specifically about gayngst and unrequited love.
And some of their issues of late, are the lowest rated in years of the manga magazine running.
Hard to believe given that they just went monthly but I'm not in the know these days, so I guess I'll take your word for it.