It does make sense within the rules of the Road Runner universe. I'm afraid you might not be ready to hear this but neither the author of this comic nor Zun wrote for Looney Tunes and their respective stories follow very different rules.
That being said, the fact that your theory doesn't make sense is not the issue. What I'm saying is that my theory makes more sense than yours.
^
Now, ZUN may not write Looney Tunes, but a good case could be made that Kezune does: http://danbooru.donmai.us/posts/1826538
Remilia simply is that stupid.(Patchouli isn't — she's just amused by these shenanigans.)
God damn it Maki.... You gotta choose who you are going to be with >.>
Not big on Harems female or male, lesbian or gay... I hate all type of harems. It's like a never ending chain of love triangles and I can only handle so much....
I usually avoid non-canon pairings but I have a thing for Mikasa x Annie, I admit. I can easily imagine their silent rivalry developing into mutual fascination and then passionate love.